Publications

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2024
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Ablative fractional CO2 laser treatment promotes wound healing phenotype in skin macrophages

Wiinberg, Martin ; Andresen, Thomas L. ; Haedersdal, Merete ; Olesen, Uffe H.
in: Lasers in Surgery and Medicine, vol: 56, issue: 3, pages: 270-278

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2024     |    DOI: https://doi.org/10.1002/lsm.23772

 

A versatile method for conjugating lipid nanoparticles on T cells through combination of click chemistry and metabolic glycoengineering

Li, Xin ; Weller, Sven ; Clergeaud, Gael ; Andresen, Thomas L.
in: Biotechnology Journal, vol: 19, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2024     |    DOI: https://doi.org/10.1002/biot.202300339

 

Fully Biobased Adhesive from Chitosan and Tannic Acid with High Water Resistance

Qie, Runtian ; Zajforoushan Moghaddam, Saeed ; Thormann, Esben
in: ACS Sustainable Chemistry and Engineering, vol: 12, pages: 4456−4463

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2024     |    DOI: https://doi.org/10.1021/acssuschemeng.3c07306

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Influence of different conjugation methods for activating antibodies on polymeric nanoparticles

Weller, Sven ; Li, Xin ; Petersen, Lars R. ; Kempen, Paul ; Clergeaud, Gael ; Andresen, Thomas L.
in: International Immunopharmacology, vol: 129

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2024     |    DOI: https://doi.org/10.1016/j.intimp.2024.111643

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Interactions of oral permeation enhancers with lipid membranes in simulated intestinal environments

Larsen, Nanna Wichmann ; Kostrikov, Serhii ; Hansen, Morten Borre ; Hjørringgaard, Claudia Ulrich ; Larsen, Niels Bent ; Andresen, Thomas Lars ; Kristensen, Kasper
in: International Journal of Pharmaceutics, vol: 654

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2024     |    DOI: https://doi.org/10.1016/j.ijpharm.2024.123957

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Laser-assisted topical delivery of vismodegib reduces hedgehog gene expression in human basal cell carcinomas in vivo

Olesen, Uffe H. ; Pedersen, Kristian Kåber ; Togsverd-Bo, Katrine ; Biskup, Edyta ; Nielsen, Anni Linnet ; Jackerott, Malene ; Clergeaud, Gael ; Andresen, Thomas L. ; Haedersdal, Merete
in: Lasers in Surgery and Medicine, vol: 56, issue: 3, pages: 239-248

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2024     |    DOI: https://doi.org/10.1002/lsm.23766

 

Measuring the Salt Content of Sweat inside a Sweat-Absorbing Skin Adhesive

Eiler, Johannes ; Ehtiati, Koosha ; Sørensen, Ingrid Eklundh ; Thormann, Esben
in: ACS Applied Bio Materials, vol: 7, pages: 452-461

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2024     |    DOI: https://doi.org/10.1021/acsabm.3c01051

 

Nuclear isomers in medicine

Jensen, Mikael
in: European Physical Journal: Special Topics

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2024     |    DOI: https://doi.org/10.1140/epjs/s11734-024-01129-y

 

Reducing Ice Adhesion to Polyelectrolyte Surfaces by Counterion-Mediated Nonfrozen Hydration Water

Biro, Robert A. ; Tyrode, Eric C. ; Thormann, Esben
in: ACS Applied Materials and Interfaces, vol: 16, pages: 21356-21365

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2024     |    DOI: https://doi.org/10.1021/acsami.4c02434

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Transcriptional Host Responses to Infection with Streptococcus suis in a Porcine Precision-Cut Lung Slice Model: Between-Strain Differences Suggest Association with Virulence Potential

Weldearegay, Yenehiwot Berhanu ; Brogaard, Louise ; Nerlich, Andreas ; Schaaf, Désirée ; Heegaard, Peter M. H. ; Valentin-Weigand, Peter
in: Pathogens, vol: 13, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2024     |    DOI: https://doi.org/10.3390/pathogens13010004

2023
 

A Biomimetic Water-Resistant Adhesive Based on ϵ-Polylysine/Tannic Acid Complexation

Kang, Junjie ; Zajforoushan Moghaddam, Saeed ; Larsen, René Wugt ; Thormann, Esben
in: ACS Applied Polymer Materials, vol: 5, pages: 8216−8222

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acsapm.3c01400

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Active Transport and Ocular Distribution of Intravitreally Injected Liposomes

Eriksen, Anne Zebitz ; Melander, Fredrik ; Eriksen, Grace de Malona ; Kempen, Paul Joseph ; Kjaer, Andreas ; Andresen, Thomas Lars ; Urquhart, Andrew James
in: Translational Vision Science and Technology, vol: 12, issue: 8

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1167/tvst.12.8.20

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A Curable Underwater Adhesive Based on Poly(propylene oxide) and Tannic Acid Coacervate

Qie, Runtian ; Zajforoushan Moghaddam, Saeed ; Thormann, Esben
in: ACS Applied Polymer Materials, vol: 5, issue: 3, pages: 1646-1650

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acsapm.2c02018

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Cs-131 as an experimental tool for the investigation and quantification of the radiotoxicity of intracellular Auger decays in vitro

Fredericia, Pil M. ; Siragusa, Mattia ; Köster, Ulli ; Severin, Gregory ; Groesser, Torsten ; Jensen, Mikael
in: International Journal of Radiation Biology, vol: 99, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1080/09553002.2020.1787541

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Dopamine-Assisted Layer-by-Layer Deposition Providing Coatings with Controlled Thickness, Roughness, and Functional Properties

Qie, Runtian ; Zajforoushan Moghaddam, Saeed ; Thormann, Esben
in: ACS Omega, vol: 8, pages: 2965−2972

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acsomega.2c05620

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Engineered substrates incapable of induction of chondrogenic differentiation compared to the chondrocyte imprinted substrates

Taheri, Shiva ; Ghazali, Zahra Sadat ; Montazeri, Leila ; Ebrahim, Fatemeh Ale ; Javadpour, Jafar ; Kamguyan, Khorshid ; Thormann, Esben ; Renaud, Philippe ; Bonakdar, Shahin
in: Biomedical Materials (Bristol), vol: 18, issue: 2

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1088/1748-605X/acb5d7

 

Fibrin Adsorption on Cardiovascular Biomaterials and Medical Devices

Nzulumike, Achebe N O ; Thormann, Esben
in: ACS Applied Bio Materials, vol: 6, issue: 7, pages: 2667–2676

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acsabm.2c01057

 

Fibrin formation and fractal organization at cationic, anionic, and zwitterionic polymer coated interfaces

Nzulumike, Achebe N. O. ; Biro, Robert A ; Thormann, Esben
in: Soft Matter, vol: 19, pages: 4360-4368

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1039/d2sm01533a

 

Formulation and characterization of insulin nanoclusters for a controlled release

Danielsen, Mia ; Kempen, Paul Joseph ; Andresen, Thomas Lars ; Urquhart, Andrew James
in: International Journal of Biological Macromolecules, vol: 235

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1016/j.ijbiomac.2023.123658

 

Fragmentation of Hydrophilic Guidewire Coatings During Neuroendovascular Therapy

Dahl, Rasmus Holmboe ; Larsen, René Wugt ; Thormann, Esben ; Benndorf, Goetz
in: Clinical Neuroradiology, vol: 33, pages: 793–799

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1007/s00062-023-01283-1

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Immunogenicity of Bacillus Calmette-Guérin in pigs: potential as a translational model of non-specific effects of BCG

Jensen, Kristoffer Jarlov ; Hansen, Mette Sif ; Skovgaard, Kerstin ; Svensson, Erik ; Larsen, Lars Erik ; Heegaard, Peter M.H. ; Benn, Christine Stabell ; Jungersen, Gregers
in: Frontiers in Immunology, vol: 14

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.3389/fimmu.2023.1219006

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Improved procedures for production and purification of 135La from enriched [135Ba]BaCO3 on a 16.5 MeV cyclotron

Pedersen, Kristina Søborg ; Deville, Claire ; Søndergaard, Ursula ; Jensen, Mikael ; Jensen, Andreas I.
in: Applied Radiation and Isotopes, vol: 192

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1016/j.apradiso.2022.110612

 

Influence of Ionic Strength and Specific Ion Effects on Polyelectrolyte Multilayer Films with pH-Responsive Behavior

Hegaard, Frederik ; Thormann, Esben
in: Langmuir, vol: 39, issue: 14, pages: 5012-5020

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acs.langmuir.2c03515

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Influence of vitamin D metabolites on vitamin D status, immunity and gut health of piglets

Madsen, Pernille A. ; Etheve, Stephane ; Heegaard, Peter M.H. ; Skovgaard, Kerstin ; Mary, Anne-Lise ; Litta, Gilberto ; Lauridsen, Charlotte
in: Veterinary Immunology and Immunopathology, vol: 257

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1016/j.vetimm.2023.110557

 

Investigating Generation of Antibodies against the Lipid Nanoparticle Vector Following COVID-19 Vaccination with an mRNA Vaccine

Münter, Rasmus ; Sørensen, Erik ; Hasselbalch, Rasmus B. ; Christensen, Esben ; Nielsen, Susanne D. ; Garred, Peter ; Ostrowski, Sisse R. ; Bundgaard, Henning ; Iversen, Kasper K. ; Andresen, Thomas L. ; Larsen, Jannik B.
in: Molecular Pharmaceutics, vol: 20, issue: 7, pages: 3356-3366

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acs.molpharmaceut.2c01036

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Ion-Specific Antipolyelectrolyte Effect on the Swelling Behavior of Polyzwitterionic Layers

Hegaard, Frederik ; Biro, Robert ; Ehtiati, Koosha ; Thormann, Esben
in: Langmuir, vol: 39, issue: 4, pages: 1456-1464

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acs.langmuir.2c02798

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Mitochondrial reactive oxygen species modify extracellular vesicles secretion rate

Nørgård, Mikkel ; Lund, Philip M. ; Kalisi, Nazmie ; Andresen, Thomas L. ; Larsen, Jannik B. ; Vogel, Stefan ; Svenningsen, Per
in: FASEB BioAdvances, vol: 5, issue: 9, pages: 355-366

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1096/fba.2023-00053

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Neoadjuvant Gold Nanoshell-Based Photothermal Therapy Combined with Liposomal Doxorubicin in a Mouse Model of Colorectal Cancer

Simón, Marina ; Jørgensen, Jesper Tranekjær ; Norregaard, Kamilla ; Henriksen, Jonas Rosager ; Clergeaud, Gael ; Andresen, Thomas L. ; Hansen, Anders Elias ; Kjaer, Andreas
in: International Journal of Nanomedicine, vol: 18, pages: 829-841

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.2147/IJN.S389260

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Quantitative live-cell imaging of lipidated peptide transport through an epithelial cell layer

Hundahl, Adam Coln ; Weller, Arjen ; Larsen, Jannik Bruun ; Hjørringgaard, Claudia U. ; Hansen, Morten B. ; Mündler, Ann Kathrin ; Knuhtsen, Astrid ; Kristensen, Kasper ; Arnspang, Eva C. ; Andresen, Thomas Lars ; Mortensen, Kim I. ; Marie, Rodolphe
in: Journal of controlled release, vol: 355, pages: 122-134

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1016/j.jconrel.2023.01.066

 

Self-Cross-Linkable Chitosan-Alginate Complexes Inspired by Mussel Glue Chemistry

Kang, Junjie ; Zajforoushan Moghaddam, Saeed ; Thormann, Esben
in: Langmuir, vol: 39, pages: 15499−15506

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acs.langmuir.3c01750

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Signatures of T cell immunity revealed using sequence similarity with TCRDivER algorithm

Vujović, Milena ; Marcatili, Paolo ; Chain, Benny ; Kaplinsky, Joseph ; Andresen, Thomas Lars
in: Communications Biology, vol: 6, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1038/s42003-023-04702-8

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Small-molecule modulators of tumor necrosis factor signaling

Chédotal, Henri ; Narayanan, Dilip ; Povlsen, Katrine ; Gotfredsen, Charlotte H. ; Brambilla, Roberta ; Gajhede, Michael ; Bach, Anders ; Clausen, Mads H.
in: Drug Discovery Today, vol: 28, issue: 6

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1016/j.drudis.2023.103575

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Studying how administration route and dose regulates antibody generation against LNPs for mRNA delivery with single-particle resolution

Münter, Rasmus ; Christensen, Esben ; Andresen, Thomas L. ; Larsen, Jannik B.
in: Molecular Therapy - Methods and Clinical Development, vol: 29, pages: 450-459

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1016/j.omtm.2023.05.008

 

Sulochrins and alkaloids from a fennel endophyte Aspergillus sp. FVL2

Shaaban, Mohamed ; Abdel-Razek, Ahmed S. ; Previtali, Viola ; Clausen, Mads Hartvig ; Gotfredsen, Charlotte H. ; Laatsch, Hartmut ; Ding, Ling
in: Natural Product Research, vol: 37, issue: 8, pages: 1310-1320

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1080/14786419.2021.2005054

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The emergence and diversification of a zoonotic pathogen from within the microbiota of intensively farmed pigs

Murray, Gemma G.R. ; Hossain, A. S.Md Mukarram ; Miller, Eric L. ; Bruchmann, Sebastian ; Balmer, Andrew J. ; Matuszewska, Marta ; Herbert, Josephine ; Hadjirin, Nazreen F. ; Mugabi, Robert ; Li, Ganwu ; Ferrando, Maria Laura ; de Oliveira, Isabela Maria Fernandes ; Nguyen, Thanh ; Yen, Phung L.K. ; Phuc, Ho D. ; Moe, Aung Zaw ; Wai, Thiri Su ; Gottschalk, Marcelo ; Aragon, Virginia ; Valentin-Weigand, Peter ; Heegaard, Peter M.H. ; Vrieling, Manouk ; Maw, Min Thein ; Myint, Hnin Thidar ; Win, Ye Tun ; Hoa, Ngo Thi ; Bentley, Stephen D. ; Clavijo, Maria J. ; Wells, Jerry M. ; Tucker, Alexander W. ; Weinert, Lucy A.
in: Proceedings of the National Academy of Sciences of the United States of America, vol: 120, issue: 47

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1073/pnas.2307773120

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Transparent and Cell-Guiding Cellulose Nanofiber 3D Printing Bioinks

Radeke, Carmen ; Pons, Raphaël ; Mihajlovic, Marko ; Knudsen, Jonas R. ; Butdayev, Sarkhan ; Kempen, Paul J. ; Segeritz, Charis Patricia ; Andresen, Thomas L. ; Pehmøller, Christian K. ; Jensen, Thomas E. ; Lind, Johan U.
in: ACS Applied Materials and Interfaces, vol: 15, pages: 2564−2577

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acsami.2c16126

 

Tuning the Framework of Thioether-Functionalized Polyazamacrocycles

Tosato, Marianna ; Franchi, Sara ; Dalla Tiezza, Marco ; Orian, Laura ; Gyr, Thomas ; Alker, André ; Zanoni, Giordano ; Pastore, Paolo ; Andrighetto, Alberto ; Köster, Ulli ; Jensen, Mikael ; Mäcke, Helmut ; Asti, Mattia ; Di Marco, Valerio
in: Inorganic Chemistry, vol: 62, issue: 50, pages: 20777-20790

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2023     |    DOI: https://doi.org/10.1021/acs.inorgchem.3c02456

2022
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Accelerated blood clearance and hypersensitivity by PEGylated liposomes containing TLR agonists

Stavnsbjerg, Camilla ; Christensen, Esben ; Münter, Rasmus ; Henriksen, Jonas R. ; Fach, Matthias ; Parhamifar, Ladan ; Christensen, Camilla ; Kjaer, Andreas ; Hansen, Anders E. ; Andresen, Thomas L.
in: Journal of controlled release, vol: 342, pages: 337-344

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.jconrel.2021.12.033

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A Concise Total Synthesis of the Fungal Isoquinoline Alkaloid TMC-120B

Haidar, Ahmad K. ; Kjeldsen, Niels D. ; Troelsen, Nikolaj S. ; Previtali, Viola ; Lundquist, Kasper P. ; Larsen, Thomas O. ; Clausen, Mads H.
in: Molecules, vol: 27, issue: 2

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.3390/molecules27020521

 

Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology

Rydbirk, Rasmus ; Østergaard, Ole ; Folke, Jonas ; Hempel, Casper ; DellaValle, Brian ; Andresen, Thomas L. ; Løkkegaard, Annemette ; Hejl, Anne Mette ; Bode, Matthias ; Blaabjerg, Morten ; Møller, Mette ; Danielsen, Erik H. ; Salvesen, Lisette ; Starhof, Charlotte C. ; Bech, Sara ; Winge, Kristian ; Rungby, Jørgen ; Pakkenberg, Bente ; Brudek, Tomasz ; Olsen, Jesper V. ; Aznar, Susana
in: Cellular and Molecular Life Sciences, vol: 79, issue: 6

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1007/s00018-022-04378-z

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Cell surface-tethered IL-12 repolarizes the tumor immune microenvironment to enhance the efficacy of adoptive T cell therapy

Jones, Douglas S. ; Nardozzi, Jonathan D. ; Sackton, Katharine L. ; Ahmad, Gulzar ; Christensen, Esben ; Ringgaard, Lars ; Chang, De-Kuan ; Jaehger, Ditte E. ; Konakondla, Jacob V. ; Wiinberg, Martin ; Stokes, Katherine L. ; Pratama, Alvin ; Sauer, Karsten ; Andresen, Thomas L.
in: Science Advances, vol: 8, issue: 17

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1126/sciadv.abi8075

 

Cyclic Citrullinated Peptide Aptamer Treatment Attenuates Collagen-Induced Arthritis

Khatri, Sangita ; Hansen, Jonas ; Pedersen, Nadia Bom ; Brandt-Clausen, Idamarie Palsbom ; Gram-Nielsen, Sanne ; Mendes, Ana C. ; Chronakis, Ioannis S. ; Keiding, Ulrik Bering ; Catrina, Anca I. ; Rethi, Bence ; Clausen, Mads Hartvig ; Kragstrup, Tue ; Astakhova, Kira
in: Biomacromolecules, vol: 23, issue: 5, pages: 2126-2137

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1021/acs.biomac.2c00144

 

DEVELOPMENT OF A QUANTITATIVE IMMUNOASSAY FOR SERUM HAPTOGLOBIN AS A PUTATIVE DISEASE MARKER IN THE SOUTHERN WHITE RHINOCEROS (CERATOTHERIUM SIMUM SIMUM)

Petersen, Henrik H. ; Stenbak, Rikke ; Blaabjerg, Camilla ; Krogh, Anne K. H. ; Bertelsen, Mads F. ; Buss, Peter ; Heegaard, Peter M. H.
in: Journal of Zoo and Wildlife Medicine, vol: 53, issue: 1, pages: 141-152

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1638/2020-0010

 

Enhancing Adoptive Cell Therapy by T Cell Loading of SHP2 Inhibitor Nanocrystals before Infusion

Li, Xin ; Halldórsdóttir, Hólmfridur R. ; Weller, Sven ; Colliander, Anna ; Bak, Martin ; Kempen, Paul ; Clergeaud, Gael ; Andresen, Thomas L.
in: ACS Nano, vol: 16, issue: 7, pages: 10918-10930

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1021/acsnano.2c03311

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Enhancing the sweat resistance of sunscreens

Keshavarzi, Fatemeh ; Knudsen, Nina Østergaard ; Komjani, Niloufarsadat Mirmahdi ; Ebbesen, Morten F. ; Brewer, Jonathan R. ; Jafarzadeh, Shadi ; Thormann, Esben
in: Skin Research and Technology, vol: 28, issue: 2

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1111/srt.13115

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Experimental infection of high health pigs with porcine circovirus type 2 (PCV2) and Lawsonia intracellularis

Hansen, Mette S. ; Jensen, Tim K. ; Hjulsager, Charlotte K. ; Angen, Øystein ; Riber, Ulla ; Nielsen, Jens ; Heegaard, Peter M.H. ; Larsen, Lars E.
in: Frontiers in Veterinary Science, vol: 9

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.3389/fvets.2022.994147

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Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening

Lee, Sang-Woo ; Tran, Kim Tai ; Vazquez-Uribe, Ruben ; Gotfredsen, Charlotte Held ; Clausen, Mads Hartvig ; Mendez, Blanca Lopez ; Montoya, Guillermo ; Bach, Anders ; Sommer, Morten Otto Alexander
in: Journal of Medicinal Chemistry, vol: 65, issue: 4, pages: 3266–3305

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1021/acs.jmedchem.1c01834

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Innate antiviral responses in porcine nasal mucosal explants inoculated with influenza A virus are comparable with responses in respiratory tissues after viral infection

Starbæk, Sofie M.R. ; Rask Andersen, Malene ; Brogaard, Louise ; Spinelli, Anna ; Rapson, Victoria ; Aagaard Glud, Helena ; Larsen, Lars E. ; Heegaard, Peter M.H. ; Nauwynck, Hans ; Skovgaard, Kerstin
in: Immunobiology, vol: 227

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.imbio.2022.152192

 

Making Protein-Based Adhesives Water Resistant: Role of Protein Water Solubility, Galloyl Modification, and Complexation

Moghaddam, Saeed Zajforoushan ; Qie, Runtian ; Thormann, Esben
in: ACS Applied Polymer Materials, vol: 4, issue: 1, pages: 18–23

Type: Letter (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1021/acsapm.1c01089

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Matrix effect in tumor lysates – Does it affect your cytokine ELISA and multiplex analyses?

Stavnsbjerg, Camilla ; Jørgensen, Jennifer Solgaard ; Engel, Trine Bjørnbo ; Brus, Anja ; Ringgaard, Lars ; Hansen, Anders Elias ; Kjaer, Andreas ; Andresen, Thomas Lars
in: Journal of Immunological Methods, vol: 500

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.jim.2021.113177

 

Polytetrafluoroethylene coating fragments during neuroendovascular therapy

Dahl, Rasmus Holmboe ; Larsen, René Wugt ; Thormann, Esben ; Benndorf, Goetz
in: Interventional Neuroradiology, vol: 28, issue: 1, pages: 16-21

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1177/15910199211015127

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Quantifying the heterogeneity of enzymatic dePEGyaltion of liposomal nanocarrier systems

Eliasen, Rasmus ; Lars Andresen, Thomas ; Bruun Larsen, Jannik
in: European Journal of Pharmaceutics and Biopharmaceutics, vol: 171, pages: 80-89

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.ejpb.2021.12.013

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Sortilin regulates blood-brain barrier integrity

Toth, Andrea E. ; Helms, Hans C. ; Harazin, Andras ; Johnsen, Kasper B. ; Goldeman, Charlotte ; Burkhart, Annette ; Thomsen, Maj S. ; Kempen, Paul J. ; Klepe, Adrian ; Lipka, Dora V. ; Møller, Peter L. ; Andresen, Thomas L. ; Nyegaard, Mette ; Moos, Torben ; Brodin, Birger ; Nielsen, Morten S.
in: FEBS Journal, vol: 289, issue: 4, pages: 1062-1079

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1111/febs.16225

 

Specific Counterion Effects on the Swelling Behavior of Strong Polyelectrolyte Brushes

Ehtiati, Koosha ; Moghaddam, Saeed Z. ; Klok, Harm-Anton ; Daugaard, Anders E. ; Thormann, Esben
in: Macromolecules, vol: 55, issue: 12, pages: 5123–5130

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1021/acs.macromol.2c00411

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Stiffness control in dual color tomographic volumetric 3D printing

Wang, Bin ; Engay, Einstom ; Stubbe, Peter R. ; Moghaddam, Saeed Z. ; Thormann, Esben ; Almdal, Kristoffer ; Islam, Aminul ; Yang, Yi
in: Nature Communications, vol: 13, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1038/s41467-022-28013-4

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Synthesis and evaluation of hydrogen peroxide sensitive tofacitinib prodrugs

Previtali, Viola ; Keiding, Ulrik Bering ; Olsen, Asger Hegelund ; Peiró Cadahía, Jorge ; Clausen, Anne Skovsbo ; Kjaer, Andreas ; Andresen, Thomas Lars ; Hansen, Anders Elias ; Clausen, Mads Hartvig
in: European Journal of Medicinal Chemistry Reports, vol: 4

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.ejmcr.2021.100019

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Targeting undruggable carbohydrate recognition sites through focused fragment library design

Shanina, Elena ; Kuhaudomlarp, Sakonwan ; Siebs, Eike ; Fuchsberger, Felix F. ; Denis, Maxime ; Gomes, Priscila da Silva Figueiredo Celestino ; Clausen, Mads H. ; Seeberger, Peter H. ; Rognan, Didier ; Titz, Alexander ; Imberty, Anne ; Rademacher, Christoph
in: Communications Chemistry, vol: 5, issue: 1

Type: Letter (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1038/s42004-022-00679-3

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Towards in vivo applications of 111Ag perturbed angular correlation of γ-rays (PAC) spectroscopy

Tosato, Marianna ; Asti, Mattia ; Di Marco, Valerio ; Jensen, Marianne L. ; Schell, Juliana ; Dang, Thien Thanh ; Köster, Ulli ; Jensen, Mikael ; Hemmingsen, Lars
in: Applied Radiation and Isotopes, vol: 190

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.apradiso.2022.110508

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Tying Up a Loose End

Balogh, Ria K. ; Gyurcsik, Béla ; Jensen, Mikael ; Thulstrup, Peter W. ; Köster, Ulli ; Christensen, Niels Johan ; Jensen, Marianne L. ; Hunyadi-Gulyás, Éva ; Hemmingsen, Lars ; Jancsó, Attila
in: ChemBioChem, vol: 23, issue: 16

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1002/cbic.202200290

2021
  PDF

ABCG transporters export cutin precursors for the formation of the plant cuticle

Elejalde-Palmett, Carolina ; Martinez San Segundo, Ignacio ; Garroum, Imène ; Charrier, Laurence ; De Bellis, Damien ; Mucciolo, Antonio ; Guerault, Aurore ; Liu, Jie ; Zeisler-Diehl, Viktoria ; Aharoni, Asaph ; Schreiber, Lukas ; Bakan, Bénédicte ; Clausen, Mads Hartvig ; Geisler, Markus ; Nawrath, Christiane
in: Current Biology, vol: 31, issue: 10, pages: 2111-2123.e9

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.cub.2021.02.056

 

A generic protocol to immobilize lipopolysaccharides on microbeads for multiplex analysis

Boas, Ulrik ; Sørensen, Mads B. ; Andresen, Lars O. ; Berger, Sanne S.
in: Analytical Methods, vol: 13, issue: 22, pages: 2485-2494

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1039/d1ay00327e

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Antimicrobial PDMS Surfaces Prepared through Fastand Oxygen-Tolerant SI-SARA-ATRP, Using Na2SO3 as a Reducing Agent

Andersen, Christian ; Zverina, Libor ; Ehtiati, Koosha ; Thormann, Esben ; Mordhorst, Hanne ; Pamp, Sünje J. ; Madsen, Niels J. ; Daugaard, Anders E.
in: ACS Omega, vol: 6, issue: 22, pages: 14551–14558

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1021/acsomega.1c01611

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Anti-pd-1 therapy with adjuvant ablative fractional laser improves anti-tumor response in basal cell carcinomas

Olesen, Uffe Høgh ; Wiinberg, Martin ; Lerche, Catharina Margrethe ; Jæhger, Ditte Elisabeth ; Andresen, Thomas Lars ; Haedersdal, Merete
in: Cancers, vol: 13, issue: 24

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.3390/cancers13246326

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A pH-responsive polyelectrolyte multilayer film with tunable interfacial properties

Jiang, Tao ; Moghaddam, Saeed Zajforoushan ; Thormann, Esben
in: Polymer, vol: 214

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.polymer.2020.123367

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A pipeline towards the biochemical characterization of the arabidopsis gt14 family

Xuan, Lingling ; Zhang, Jie ; Lu, Weitai ; Gluza, Pawel ; Ebert, Berit ; Kotake, Toshihisa ; Lu, Mengzhu ; Zhang, Yuan ; Clausen, Mads Hartvig ; Johnson, Kim L. ; Doblin, Monika S. ; Heazlewood, Joshua L. ; Bacic, Antony ; Song, Lili ; Zeng, Wei
in: International Journal of Molecular Sciences , vol: 22, issue: 3

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.3390/ijms22031360

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Applying flow cytometry to identify the modes of action of membrane-active peptides in a label-free and high-throughput fashion

Wichmann, Nanna ; Lund, Philip M. ; Hansen, Morten B. ; Hjørringgaard, Claudia U. ; Larsen, Jannik B. ; Kristensen, Kasper ; Andresen, Thomas L. ; Simonsen, Jens B.
in: B B A - Biomembranes, vol: 864, issue: 2

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.bbamem.2021.183820

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Carbohydrate based biomarkers enable hybrid near infrared fluorescence and64cu based radio-guidance for improved surgical precision

Wang, Wenbo ; Hansen, Anders E. ; Sun, Hongmei ; Fliedner, Frederikke P. ; Kjaer, Andreas ; Jensen, Andreas I. ; Andresen, Thomas L. ; Henriksen, Jonas R.
in: Nanotheranostics, vol: 5, issue: 4, pages: 448-460

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.7150/ntno.60295

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Cell-imprinted substrates: in search of nanotopographical fingerprints that guide stem cell differentiation

Kamguyan, Khorshid ; Moghaddam, Saeed Zajforoushan ; Nazbar, Abolfazl ; Haramshahi, Seyyed Mohammad Amin ; Taheri, Shiva ; Bonakdar, Shahin ; Thormann, Esben
in: Nanoscale Advances, vol: 3, issue: 2, pages: 333-338

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1039/D0NA00692K

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Crucial Nonelectrostatic Effects on Polyelectrolyte Brush Behavior

Ehtiati, Koosha ; Moghaddam, Saeed Z. ; Daugaard, Anders E. ; Thormann, Esben
in: Macromolecules, vol: 54, issue: 7, pages: 3388-3394

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1021/acs.macromol.0c02526

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Dual-Material 3D-Printed Intestinal Model Devices with Integrated Villi-like Scaffolds

Taebnia, Nayere ; Zhang, Rujing ; Kromann, Emil B ; Dolatshahi-Pirouz, Alireza ; Andresen, Thomas L ; Larsen, Niels B.
in: ACS Applied Materials and Interfaces, vol: 13, issue: 49, pages: 58434–58446

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1021/acsami.1c22185

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Dynamics of local gene regulations in synovial fluid leukocytes from horses with lipopolysaccharide-induced arthritis

Walters, Marie ; Skovgaard, Kerstin ; Andersen, Pia Haubro ; Heegaard, Peter M.H. ; Jacobsen, Stine
in: Veterinary Immunology and Immunopathology, vol: 241

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.vetimm.2021.110325

 

Effective Intratumoral Retention of [103Pd]AuPd Alloy Nanoparticles Embedded in Gel-Forming Liquids Paves the Way for New Nanobrachytherapy

Fach, Matthias ; Fliedner, Frederikke P. ; Kempen, Paul J. ; Melander, Fredrik ; Hansen, Anders E. ; Bruun, Linda M. ; Köster, Ulli ; Sporer, Emanuel ; Kjær, Andreas ; Andresen, Thomas L. ; Jensen, Andreas I. ; Henriksen, Jonas R.
in: Advanced Healthcare Materials, vol: 10, issue: 10

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1002/adhm.202002009

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Effect of apoA-I PEGylation on the Biological Fate of Biomimetic High-Density Lipoproteins

Pedersbæk, Dennis ; Krogager, Louise ; Albertsen, Camilla Hald ; Ringgaard, Lars ; Hansen, Anders E. ; Jønsson, Katrine ; Larsen, Jannik B. ; Kjær, Andreas ; Andresen, Thomas L. ; Simonsen, Jens B.
in: ACS Omega, vol: 6, issue: 1, pages: 871-880

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1021/acsomega.0c05468

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Engineering the substrate binding site of the hyperthermostable archaeal endo-β-1,4-galactanase from Ignisphaera aggregans

Muderspach, Sebastian J. ; Fredslund, Folmer ; Volf, Verena ; Poulsen, Jens-Christian Navarro ; Blicher, Thomas H. ; Clausen, Mads Hartvig ; Rasmussen, Kim Krighaar ; Krogh, Kristian B. R. M. ; Jensen, Kenneth ; Lo Leggio, Leila
in: Biotechnology for Biofuels, vol: 14, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1186/s13068-021-02025-6

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Enhancing adoptive CD8 T cell therapy by systemic delivery of tumor associated antigens

Jæhger, Ditte E. ; Hübbe, Mie L. ; Kræmer, Martin K. ; Clergeaud, Gael ; Olsen, André V. ; Stavnsbjerg, Camilla ; Wiinholt, Mette N. ; Kjær, Andreas ; Henriksen, Jonas R. ; Hansen, Anders E. ; Andresen, Thomas L.
in: Scientific Reports, vol: 11, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1038/s41598-021-99347-0

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Focused Ultrasound and Microbubble Treatment Increases Delivery of Transferrin Receptor-Targeting Liposomes to the Brain

Olsman, Marieke ; Sereti, Viktoria ; Mühlenpfordt, Melina ; Johnsen, Kasper Bendix ; Andresen, Thomas Lars ; Urquhart, Andrew James ; Davies, Catharina de Lange
in: Ultrasound in Medicine and Biology, vol: 47, issue: 5, pages: 1343-1355

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.ultrasmedbio.2021.01.014

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Fragment-based drug discovery for RNA targets

Lundquist, Kasper Plenov ; Panchal, Vipul ; Gotfredsen, Charlotte Held ; Brenk, Ruth ; Clausen, Mads Hartvig
in: ChemMedChem, vol: 16, issue: 17, pages: 2588-2603

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1002/cmdc.202100324

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Infant formula based on milk fat affects immune development in both normal birthweight and fetal growth restricted neonatal piglets

Bæk, Ole ; Skadborg, Karina ; Muk, Tik ; Amdi, Charlotte ; Heegaard, Peter M.H. ; Thymann, Thomas ; Nguyen, Duc Ninh
in: Nutrients, vol: 13, issue: 10

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.3390/nu13103310

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In vitro skin model for characterization of sunscreen substantivity upon perspiration

Keshavarzi, Fatemeh ; Ø. Knudsen, Nina ; Brewer, Jonathan R. ; Ebbesen, Morten F. ; M. Komjani, Niloufarsadat ; Moghaddam, Saeed Z. ; Jafarzadeh, Shadi ; Thormann, Esben
in: International Journal of Cosmetic Science, vol: 43, issue: 3, pages: 359-371

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1111/ics.12703

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Isolation methods commonly used to study the liposomal protein corona suffer from contamination issues

Kristensen, Kasper ; Münter, Rasmus ; Kempen, Paul J. ; Thomsen, Mikkel E. ; Stensballe, Allan ; Andresen, Thomas L.
in: Acta Biomaterialia, vol: 130, pages: 460-472

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.actbio.2021.06.008

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Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors

Kostrikov, Serhii ; Johnsen, Kasper B. ; Braunstein, Thomas H. ; Gudbergsson, Johann M. ; Fliedner, Frederikke P. ; Obara, Elisabeth A.A. ; Hamerlik, Petra ; Hansen, Anders E. ; Kjaer, Andreas ; Hempel, Casper ; Andresen, Thomas L.
in: Communications Biology, vol: 4, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1038/s42003-021-02275-y

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Oxygen releasing hydrogels for beta cell assisted therapy

Toftdal, Mette Steen ; Taebnia, Nayere ; Kadumudi, Firoz Babu ; Andresen, Thomas Lars ; Frogne, Thomas ; Winkel, Louise ; Grunnet, Lars Groth ; Dolatshahi-Pirouz, Alireza
in: International Journal of Pharmaceutics, vol: 602

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.ijpharm.2021.120595

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Parameterization of the optical constants of polydopamine films for spectroscopic ellipsometry studies

Qie, Runtian ; Moghaddam, Saeed Zajforoushan ; Thormann, Esben
in: Physical Chemistry Chemical Physics, vol: 23, pages: 5516-5526

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1039/d0cp04796a

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Phosphocholine-Decorated PPI-Dendrimers Mimic Cell Membrane Phosphocholine Clusters and Tune the Innate Immune Activity of C-Reactive Protein

Boas, Ulrik ; Daoud, Mohammad Mahdi ; Meier, Sebastian ; Olsen, Tobias Hegelund ; Gehring, Kristoffer ; Juhl Mogensen, Ditte ; Heegaard, Peter M. H.
in: Biomacromolecules, vol: 22, issue: 4, pages: 1664–1674

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1021/acs.biomac.1c00085

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Photothermal therapy as adjuvant to surgery in an orthotopic mouse model of human fibrosarcoma

Simón, Marina ; Jørgensen, Jesper Tranekjær ; Melander, Fredrik ; Andresen, Thomas Lars ; Christensen, Anders ; Kjaer, Andreas
in: Cancers, vol: 13, issue: 22

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.3390/cancers13225820

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pH-Responsive Chitosan Nanofilms Crosslinked with Genipin

Miras, Jonathan ; Liu, Chao ; Blomberg, Eva ; Thormann, Esben ; Vílchez, Susana ; Esquena, Jordi
in: Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol: 616

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.colsurfa.2021.126229

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Piglet innate immune response to Streptococcus suis colonization is modulated by the virulence of the strain

Neila-Ibanez, Carlos ; Brogaard, Louise ; Pailler-Garcia, Lola ; Martinez, Jorge ; Segales, Joaquim ; Segura, Mariela ; Heegaard, Peter M. H. ; Aragon, Virginia
in: Veterinary Research, vol: 52

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1186/s13567-021-01013-w

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Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles

Kucharz, Krzysztof ; Kristensen, Kasper ; Johnsen, Kasper Bendix ; Lund, Mette Aagaard ; Lønstrup, Micael ; Moos, Torben ; Andresen, Thomas Lars ; Lauritzen, Martin Johannes
in: Nature Communications, vol: 12, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1038/s41467-021-24323-1

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Rhamnogalacturonan II - Chemical Synthesis of a Substructure Including α-2,3-Linked Kdo

Mancuso, Enzo ; Romanò, Cecilia ; Trattnig, Nino ; Gritsch, Philipp ; Kosma, Paul ; Clausen, Mads Hartvig
in: Chemistry - A European Journal, vol: 27, issue: 24, pages: 7099-7102

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1002/chem.202100837

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Small-Molecule Inhibitors of Reactive Oxygen Species Production

Sassetti, Elisa ; Clausen, Mads Hartvig ; Laraia, Luca
in: Journal of Medicinal Chemistry, vol: 64, issue: 9, pages: 5252-5275

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1021/acs.jmedchem.0c01914

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The genome of the naturally evolved obesity-prone Ossabaw miniature pig

Zhang, Yaolei ; Fan, Guangyi ; Liu, Xin ; Skovgaard, Kerstin ; Sturek, Michael ; Heegaard, Peter M.H.
in: iScience, vol: 24, issue: 9

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.isci.2021.103081